Interventional treatment of gynecologic tumors

  Gynecological tumors are tumors that occur in female reproductive organs, such as ovarian cancer, cervical cancer, endometrial cancer, uterine sarcoma, choriocarcinoma, etc. Because gynecological tumors are located deep in the pelvis and the symptoms are not typical, it is difficult for patients to detect them in the early stage. With the development of tumors, when gynecological tumors are diagnosed, they have already invaded the surrounding organs or metastasized to other parts of the body, thus many patients lose the opportunity of surgery.  With the rapid development of medicine, interventional therapy provides a new treatment opportunity for gynecologic tumor patients due to its unique treatment characteristics.  Interventional treatment of tumors generally includes arterial perfusion chemotherapy, arterial embolization and arterial embolization chemotherapy. After analyzing these blood distributions, doctors can find the real tumor blood supplying artery, i.e. the artery supplying tumor nutrition, and inject chemotherapeutic drugs directly, which will first pass through the tumor and then enter the whole body blood. The purpose of arterial chemotherapy is to increase the local drug concentration in cancer tissues, improve the killing effect on tumor cells, reduce the concentration of anti-cancer drugs in peripheral blood and decrease the toxic side effects. Arterial embolization is to inject substances directly from tumor blood supply arteries to block tumor blood supply vessels, i.e. embolic agents, in order to minimize or close tumor blood supply and cause tumor ischemia and necrosis, i.e. “starve” the tumor to death. Because malignant tumor cells divide rapidly and have great demand for blood and oxygen, and are sensitive to ischemia and hypoxia, embolization of their main blood supply arteries can cause tumor necrosis soon. Arterial embolization chemotherapy is a combination of both. Generally, chemotherapeutic drugs are injected directly from the tumor blood supply artery first, and sometimes the chemotherapeutic drugs are combined with some kind of slow-release medium to make the drugs released slowly in the tumor, and then the blood supply artery is embolized, and the ischemia and hypoxia after embolization increase the permeability of tumor cell membrane, which is more conducive to the anti-cancer drugs entering the cells to produce killing effects.  The main advantages of interventional therapy for gynecological malignant tumors are that it can reduce the volume of tumors, eliminate the tiny metastases around the cancer foci, achieve the purpose of downgrading and downgrading stage, not only make patients who lost the opportunity of surgery regain the opportunity of surgery, enhance the patient’s treatment space, but also make the surgical resection more complete and create conditions for subsequent treatment; for the treatment of postoperative recurrence of gynecological cancer tumors, it can reduce the occurrence of tumor complications and bleeding and compression symptoms, and reduce the occurrence of tumor complications and bleeding. The treatment of postoperative recurrence of gynecological cancer tumors can reduce tumor complications and bleeding, the occurrence of compression symptoms, reduce the speed of tumor development, and improve patients’ survival quality.