Those who are surgically excised clean The purpose of treatment is to control recurrence or delay or postpone recurrence After a period of treatment, if the tumor markers, clinical examination, imaging examination and PET are negative, it is called clinical complete remission If the tumor reappears during treatment, or the tumor markers do not fall or rise again after falling, it is called tumor progression After clinical complete remission, there is a reappearance of elevated tumor markers or If tumor is found in physical examination or imaging examination, it is a tumor recurrence who has not been excised by surgery (and again measurable index). Complete remission (CR): all lesions completely disappeared and lasted for more than 4 weeks Partial remission (PR): tumor lesions decreased by ≥ 50% of the product of the maximum vertical two diameters and maintained for more than 4 weeks Improvement (MR): tumor decreased by ≥ 25%, but less than 50%. Stable (SD): tumor shrinkage <25% or enlargement <25%. Progression (PD): tumor shrinkage ≥ 25% of the product of the two largest vertical diameters of the tumor lesions, or the appearance of new lesions or complete remission (CR): all lesions completely disappeared and lasted for more than 4 weeks partial remission (PR): tumor lesions shrunk ≥ 50% of the product of the two largest vertical diameters of the tumor lesions and maintained for more than 4 weeks stable (SD): tumor shrinkage or enlargement did not exceed 50%. Progression (PD): tumor lesion enlarges more than 50%, or new lesion appears.