Can ovarian cancer be prevented? Unfortunately, there is no method to prevent ovarian cancer. Once ovarian cancer is diagnosed, it is almost always in advanced stage, and very few patients can be detected in early stage, while early stage ovarian cancer can be treated well and has a high chance of being cured through surgery (more than 90%), while advanced stage has almost no chance of being cured. After surgery and chemotherapy, patients still have to suffer from recurrent ovarian cancer. Ovarian cancer mostly occurs in postmenopausal women, and the ovary is a non-functional organ after menopause, the only function is to cause trouble and grow tumors, so the treatment by gynecologic oncologists for ovarian cancer detected after menopause is very aggressive. There are still some ways to reduce the risk of ovarian cancer, the most common one is to give high priority to hereditary ovarian cancer, and family history is considered as one of the most powerful predictors of tumor. Inherited ovarian cancer is inherited in 84% and 90% of patients with mutations in the susceptibility genes BRCAI and 2, respectively, which are autosomal dominant. Accordingly, testing for BRCAl and 2 genes has become an important screening method for ovarian cancer high-risk groups. Emphasis is placed on the following groups of people 1. one person with breast cancer, especially premenopausal breast cancer (<50 years old); 2. one first-degree relative, or two second-degree relatives from the same line (paternal or maternal) with breast or ovarian cancer (at any age); 3. two or more relatives with breast and/or ovarian cancer are at high risk. BRCA genetic testing: Since the first commercial use of genetic assays in the United States in 1996, genetic testing for BRCAI and 2 mutations is now part of the clinical management of women with a family history of the disease. The only effective approach for these high-risk groups is prophylactic surgery: this includes prophylactic bilateral mastectomy, prophylactic bilateral adnexal resection, and simultaneous removal of both mammary glands and adnexa. Among them, prophylactic bilateral adnexal resection has the best protective effect, reducing the risk of ovarian cancer by about 90% (85%-100%) and breast cancer by about 50% (46%-68%) with fewer postoperative complications and side effects. We often see the daughters or sisters of ovarian cancer patients come to the clinic with ovarian cancer, and we feel sorry for these patients who are in advanced stages, because they can have surgery to prevent it but lose the opportunity. When she was asked why she didn't come to the hospital, she replied that she was afraid of finding out the disease even after seeing her family members' painful medical experience. Therefore, we must not avoid the disease and prevent it before it happens.