High blood creatinine may be related to age, strenuous exercise, kidney disease and so on. If it is caused by age, renal insufficiency, etc., it usually cannot be cured by itself, and if it is caused by strenuous exercise, etc., it usually can be cured by itself after removing the triggers. Generally with age, some older men may have high blood creatinine, which may be due to the deterioration of renal function and generally cannot be self-cured. It may also be kidney diseases, such as glomerulonephritis and hypertensive kidney injury. This causes damage to the kidneys, which affects the glomerular filtration function, and this condition also cannot be self-healed. If it is due to strenuous exercise, prompting muscle creatinine decomposition, resulting in high blood creatinine, if not accompanied by other discomforts generally remove the trigger can be self-cured. If there is any abnormality in the laboratory test, it is recommended to follow the doctor’s instructions to carry out further relevant examinations, clarify the cause with the help of the doctor, and carry out standardized treatment.