Rheumatoid arthritis has a certain genetic predisposition, but it is not necessarily passed on to the next generation. Rheumatoid arthritis is an autoimmune disease characterized by the involvement of symmetrical small joints, and is often characterized by joint pain, swelling and morning stiffness. Its development may be related to genetic, environmental and other factors. Genetic aspects: the current family survey shows that the probability of first-degree relatives of rheumatoid arthritis patients suffering from rheumatoid arthritis is 11%. A large number of studies have found that HLA-DRB1 allele mutations are associated with the development of rheumatoid arthritis. Environmental factors: It is currently believed that some infections such as bacteria, mycoplasma, viruses, or smoking are associated with the onset and progression of rheumatoid arthritis. Therefore, patients with a family history of rheumatoid arthritis have a relatively high likelihood of developing rheumatoid arthritis. However, the disease is not necessarily inherited by the next generation, and people with a family history of rheumatoid arthritis should be screened for rheumatoid arthritis disease on a regular basis. Rheumatoid arthritis patients are advised to go to the relevant departments of regular hospitals for detailed consultation and standardized treatment.