High basophils itself is not harmful, its common harm mainly comes from the diseases that cause high basophils, such as allergic diseases, hematologic diseases, tumor metastasis, parasitic infections and so on. 1. Allergic diseases: such as drug allergy, urticaria, allergic enteritis and other diseases, can cause high basophils. It can lead to allergic symptoms and body discomfort. 2. Blood system diseases: for example, basophilic leukemia, chronic granulocytic leukemia and other blood system diseases can cause high basophils, which can be life-threatening in serious cases. 3. Tumor metastasis: for example, metastasis of lung cancer, liver cancer and other tumors may also cause high basophils. Tumor will lead to a series of symptoms, which can be life-threatening in serious cases. 4. Parasitic infections: parasitic infections such as roundworm disease, schistosomiasis, hookworm disease and so on may also cause high basophils. Parasitic infections can lead to gastrointestinal and other digestive discomforts, anemia, and so on. A single value of basophil granulocytes is often unable to diagnose the disease, and it is necessary to go to the hospital in time, and the doctor will make a comprehensive judgment of the cause of the disease according to the results of the tests and carry out the treatment in order to avoid the harm.