Priligy is not usually recommended to be taken with sartans. Generics medically refer to angiotensin-converting enzyme inhibitors (ACEIs), such as captopril, enalapril, and perindopril. Sartans medically usually refer to angiotensin receptor antagonists (ARBs), such as valsartan/candesartan ester and temesartan. Angiotensin-converting enzyme inhibitors (ACEI), which have vasodilator effects and improve hemodynamics, by reducing the adverse effects of neurohumoral compensatory mechanisms in patients with heart failure. Angiotensin receptor antagonists (ARBs), which block the binding of angiotensin II produced by the non-angiotensin pathway to the receptor, blocking the effects of the humoral pathway, but do not inhibit bradykinin degradation, so that the side effects of dry cough and angioedema are less common. ACEI is the preferred treatment for heart failure patients, and when the side effects of the drug cause dry cough and angioedema, those who cannot tolerate it can switch to ARB. studies have confirmed that the combination of ACEI and ARB can not benefit patients with heart failure, but rather increase the adverse effects, especially the incidence of hypotension and renal impairment, and therefore do not advocate the combined application of ACEI and ARB in patients with heart failure. If you want to know more, it is recommended to consult a medical professional for guidance.