So far, there is no clinical evidence to prove whether nimesulide is excreted through breast milk, so it is not recommended for use in nursing women, and there is no test to prove whether it is harmful to the fetus through the placenta, so it is not recommended for use in pregnant women either. Nimesulide has some of the side effects of NSAIDs, such as possible irritation of the gastrointestinal tract and digestive tract, which may cause gastrointestinal pain, bloating, and even peptic ulcers and bleeding. In addition, Nimesulide has some damage to organs such as liver and kidney, and some pregnant women with allergies may cause skin allergic reactions, such as itching, rash and hives after taking it, so women need to disable Nimesulide during breastfeeding.