Recurrence of endometrial cancer needs to be controlled by surgical treatment, radiotherapy, targeted drugs, endocrine therapy and other measures according to specific conditions. 1. Surgery: if the recurrent lesion is small and no metastasis, the lesion can be removed by surgery. 2. Radiotherapy: if the recurrence is only localized and the patient has no history of radiotherapy, radiotherapy can be chosen; if disseminated recurrence is feasible, systemic chemotherapy can be used; commonly used chemotherapeutic drugs include paclitaxel, vincristine, cisplatin, cyclophosphamide, etc., which can effectively control the disease progression and improve the prognosis. 3. Targeted drugs: Trastuzumab, bevacizumab and other targeted drugs can effectively inhibit the malignant proliferation of tumors, shrink the lesions, improve the quality of life of patients and prolong the survival time of patients. 4. Endocrine therapy: endocrine therapy drugs commonly used in clinic include tamoxifen and medroxyprogesterone. If recurrence of endometrial cancer is found, it is recommended that patients should consult doctors in time and choose the most suitable treatment plan for themselves under the guidance of professional doctors, so as to improve the prognosis and prolong the survival period.