One case was diagnosed as Buga syndrome and six cases were diagnosed as left iliac vein compression syndrome (Cockett syndrome). Among them, the youngest patient was only 20 years old; three patients had long-term non-healing or repeated ulceration of lower limb ulcers after surgery; one patient had long-term unrelieved swelling of left lower limb after surgery. Through active efforts to treat the above patients, some of their symptoms were significantly improved, while some patients had little effect. As a doctor, seeing patients tormented by the disease and unable to do anything about it, I deeply blame myself and can’t help but reflect: is it the patient’s fault? No, definitely not. Is it the fault of peers? Nor is it. Medical institutions at all levels are not equally equipped and have limited knowledge of specialty diseases. The responsibility lies with us, and we should use advanced and various knowledge dissemination vehicles and platforms to promote awareness in the industry and educate the general public so that such regrets occur as little as possible and do not occur. Let’s get to know a common disease that causes varicose veins in the lower extremities – “iliac vein compression syndrome (Cockett syndrome)”. Iliac venous compression syndrome is a disorder of lower extremity and pelvic venous reflux caused by compression of the iliac veins (physiologic) and/or the presence of abnormal intraluminal adhesion structures. The disease was discovered in 1965 by the Cockett study, which is why some people refer to the syndrome as Cockett syndrome. The compression of the iliac vein not only causes venous reflux disorders and venous hypertension in the lower extremities, but also becomes a cause of venous insufficiency and superficial varicose veins in the lower extremities, and due to physiological factors, the left iliac vein is often compressed and can cause secondary iliac-femoral vein thrombosis, which is a potential factor for venous thrombosis in the left lower extremity and predisposes to superficial varicose veins in the left lower extremity.