Most patients with chronic atrophic gastritis are treated with active treatment, such as taking acid-suppressing and stomach-protecting medications like omeprazole and aluminum thioglycollate, and need to be actively rechecked. As long as it does not develop further or even worsen, it usually does not directly affect life expectancy. Chronic atrophic gastritis is caused by a variety of pathogenic factors, long-term chronic inflammation stimulation of the gastric mucosa caused by glandular atrophy, gastric acid, pepsin secretion becomes less, affecting the normal function of the stomach. Patients mostly suffer from epigastric discomfort, nausea, pain, fullness, loss of appetite and other symptoms. As the disease progresses, a small number of patients with atrophic gastritis may progress to gastric cancer, with a poorer prognosis. Therefore, patients with chronic atrophic gastritis should be actively treated, such as taking acid-suppressing and stomach-protecting drugs such as omeprazole and aluminum thioglycollate, which are conducive to symptomatic relief and may reduce the risk of cancer, which in turn will lead to long-term survival. Regular endoscopic review is also needed, and endoscopic mucosal dissection can be performed if necessary. The above drugs are contraindicated in case of allergy and all should be taken as prescribed by the doctor. If the patient is diagnosed with chronic atrophic gastritis, it is recommended to go to a regular hospital in a timely manner, under the guidance of the doctor to carry out targeted treatment, in order to reduce the adverse effects of the disease.