For patients with chronic hepatitis B with “major triple-positive”, after taking medication for a period of time and checking for negative HBV DNA test, normalization of ALT and negative e antigen, and then consolidating for at least 1 year and still remaining unchanged, and the total course of treatment has reached at least 2 years, medication can be considered to be discontinued; for patients with “minor triple-positive “For patients with chronic hepatitis B, after achieving negative HBV DNA test and normalization of ALT, at least 1.5 years of consolidation and still maintaining the same, and the total course of treatment has reached at least 2.5 years, can consider discontinuing the drug. Of course, if the patient has cirrhosis, he or she will need to take the drug for a long time. Therefore, you should not discontinue the medication at will, but under the guidance of your doctor, and check HBV DNA and liver function every two months for six months after discontinuation, and then every three months for at least one year of follow-up.