Closed needles are usually anesthetic, plus glucocorticoid-type drugs, do local injections to achieve the effect of local anti-inflammatory and pain relief, commonly used anesthetic is lidocaine and glucocorticoid-type drugs, commonly used is tretinoin, dexamethasone or prednisolone. If it is lidocaine, more than 1 yuan a piece, and if it is trimethoprim, dexamethasone and other drugs, are within 10 yuan, so the closed needle of the drug alone is about 10 yuan, plus the cost of closed needle treatment, the cost is between 20-30 yuan. Depending on the level of the hospital, the cost of the injection varies, if it is a tertiary hospital, the injection fee of 30 yuan, if it is a first-class hospital, the injection fee should be 20 yuan, so the cost of the entire closed needle is about 30-40 yuan.