It is possible that a 3-6 month old screaming baby has a brain problem, but it can also be a normal physical phenomenon.
If a 3-6 month old infant has occasional screaming, it is normal and is a way of expressing demands or painful discomfort. If the cry is loud, strong and ebullient, it is mostly physiologic.
If a 3-6 month old baby screams frequently and expresses high-pitched, shrill cries that are harsh and not melodious, and even cause convulsions and projectile vomiting, he or she may be suffering from brain problems, such as hypoxic-ischemic encephalopathy, encephalitis, meningitis, hydrocephalus, etc., and needs to be examined by a doctor for a further diagnosis.
There may be other reasons for 3-6 month old babies to scream, we suggest that you go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy.