Thigh armpit pain, in general, the common causes are mainly the following: First, local sebaceous cyst and infection, thigh armpit is a site where sebaceous cysts are common, once accompanied by infection will cause local pain symptoms. Patients can promote the absorption of local inflammation by applying 0.5% vital iodine gauze and gold ointment, and after the inflammation is completely absorbed, perform complete excision of epidermis-like cysts as soon as possible to avoid serious complications caused by repeated infections. Second, the larger popliteal cysts, compression of the local nerves, blood vessels and pain symptoms. At this time, it is recommended that patients consider surgical removal of popliteal cysts to relieve the local nerve and vascular compression symptoms and improve the pain in the axilla of the thigh. If the cyst is large, cyst puncture and drainage can be given first, and after aspirating the cyst fluid, the cyst can be peeled off completely along the cyst wall, which can have the effect of relieving thigh pain.