Post-ejaculation headache may be caused by over-excitement, or it may be caused by high blood pressure, neurological headache and other diseases. 1. Over-excitement: Over-excitement may occur after ejaculation, which may lead to transient insufficient supply of oxygen, resulting in post-ejaculation headache. 2. Hypertension: The cause of hypertension may be related to genetic factors, bad habits, age, and nervous excitement. The patient may have headache, arrhythmia, palpitation, tinnitus and other symptoms. After ejaculation, there may be nerve excitation, which may lead to headache. 3. Neurogenic headache: The cause of neurogenic headache may be related to factors such as nervous excitement and insomnia. The patient mainly manifests headache, and after ejaculation, the spirit will be nervous and excited, which may lead to pain. If there is a headache after ejaculation, after excluding the factor of over-excitement, it is recommended to go to the regular hospital for examination to clarify the cause.