Most patients with early gastric cancer have no obvious symptoms, while a few have nausea, vomiting or upper gastrointestinal symptoms similar to ulcer disease. Pain and weight loss are the most common clinical symptoms of progressive gastric cancer. Patients often have clear upper gastrointestinal symptoms, such as upper abdominal discomfort, fullness after eating, and as the disease progresses, upper abdominal pain increases, appetite decreases and weakness. Depending on the location of the tumor, there are also its special manifestations. Gastric cancer near the pylorus has pyloric obstruction; tumor destroying blood vessels can cause gastrointestinal bleeding symptoms such as vomiting blood and black stool. Persistent pain in the abdomen often indicates that the tumor extends beyond the stomach wall, such as enlarged supraclavicular lymph nodes, ascites, jaundice, abdominal mass, and masses in the anterior rectal recess. Patients with advanced gastric cancer may often show anemia, emaciation, malnutrition or even cachexia.