The cause of Parkinson’s disease is still unclear, but studies have concluded that genetic and environmental factors play a major role in the development of Parkinson’s disease. The details are as follows: 1, family genetic factors: such as LRRK2, PARK1 gene can lead to Parkinson’s disease, even at a young age can be affected; 2, environmental factors: exposure to toxic substances, such as long-term exposure to rotenone easy to accompany Parkinson’s disease; carbon monoxide poisoning, long-term exposure to manganese mine workers, and exposure to drugs heroin, MPDP substances, easy to lead to Parkinson’s disease.