Calf goosebumps in medicine refers to perifollicular keratosis, also known as hair keratosis, hair moss, the symptoms are mild, usually do not need special treatment, if the patient has a need for treatment or when the lesions are heavy, general treatment, drug treatment, laser treatment and other methods can be used to improve. 1. General treatment: Usually, some moisturizers such as urea ointment and cod liver oil ointment can be applied to improve the local dryness symptoms. 2. Drug treatment: for local skin keratin is relatively thick, can be used externally to exfoliate the agent treatment, such as Vitamin A acid ointment, salicylic acid ointment, etc.; the condition is more serious, can also be combined with oral vitamin A, vitamin E, or a small dose of Vitamin A acid and other drugs, to improve the symptoms. 3. Laser treatment: If the patient’s skin lesions are red, laser treatment, such as pulsed fuel laser, can be taken to relieve local symptoms. It is recommended that after diagnosis, patients should consult the dermatology department of regular hospitals, and follow the doctor’s instructions to use reasonable medication, not blindly self-medication.