The thickening of the wall of the gastric sinus may be a normal condition, gastritis, gastric ulcer, benign and malignant tumors of the stomach and other conditions. 1. Normal condition: Generally normal gastric wall can be thickened under contraction state, which is a normal condition. 2. Gastritis: If there is inflammation of the gastric sinus, the wall of the sinus will be thickened because the inflammation can lead to edema. 3. Gastric ulcer: Usually, patients with gastric ulcer often have depressed ulcers on the side of the lesser curvature of the gastric sinus, and the wall of the stomach around them may be thickened in a limited way. 4. benign and malignant tumors of the stomach: if there is irregular thickening of the wall of the stomach at the gastric sinus with narrowing of the lumen, it should be clarified that it may be caused by gastric cancer or gastric lymphoma, and tissue biopsy can be used to differentiate these two diseases. There are many other cases of thickening of the wall of the gastric sinus, it is recommended that the patient should consult a doctor in time and under the guidance of a professional doctor, carry out the relevant treatment after clarifying the cause of the disease.