Deviated nasal septum and bilateral mucosal thickening of the maxillary and sieve sinus cavities are considered to mean the presence of structural abnormalities of the nasal septum and the possibility of sinus inflammation, and belong to the terminological description of imaging. Deviated septum represents a deviation of the nasal septum from the midline or a localized protuberance in the form of a C-shape, S-shape, cusp-like vertebrae, or crest-like protuberance. It can be caused by nasal trauma, nasal or sinus tumor compression, developmental abnormalities, or genetics. It often causes nasal congestion, headache, nosebleed and other manifestations. Bilateral maxillary sinus and sieve sinus cavity mucosal thickening represents the maxillary sinus and sieve sinus may exist mucosal edema or hyperplasia, sinus cavity mucosa in the infection, allergy and the stimulation of adverse physicochemical factors, may have edema, hyperplasia changes, which in turn on the CT manifested as thickening of mucous membranes, may have runny nose, olfactory obstruction and localized pain manifestation, or may not have any discomfort. Once the examination found that the nasal septum deviation, bilateral maxillary sinus and sieve sinus cavity mucosal thickening, it is recommended to consult a professional doctor in a timely manner, and follow the doctor’s instructions to standardize the treatment.