Nutcracker syndrome does not usually lead to chronic glomerulonephritis.
The pathogenesis of Nutcracker syndrome is that adolescents, or people who are thin, usually develop hematuria and proteinuria because of the compression of the left renal vein during its return flow into the inferior vena cava through the angle formed by the abdominal aorta and the superior mesenteric artery, or the gap between the abdominal aorta and the spinal column.
Nutcracker syndrome is actually due to mechanical pressure, and there is usually no renal impairment, so it usually does not develop into chronic glomerulonephritis.
The pathogenesis of chronic glomerulonephritis is mainly related to immune-mediated inflammatory factors such as infection, in addition, non-immune non-inflammatory factors such as hypertension, massive proteinuria, and hyperlipidemia can also lead to it.
Because the pathogenesis of Nutcracker syndrome and chronic glomerulonephritis are significantly different, there is no direct causal relationship between the two, and usually, Nutcracker syndrome does not lead to chronic glomerulonephritis.
Patients with Nutcracker syndrome or chronic glomerulonephritis are advised to consult a doctor in time and follow the doctor’s instructions for standardized diagnosis and treatment.