Melanin spots on the face may be freckles, chloasma, age spots and so on, which can be removed by medication and laser. 1. Medication: To remove chloasma, you can apply topical cumeneoside cream ointment or retinoic acid cream, and you can also choose oral tranexamic acid tablets, topical hydroquinone cream, azelaic acid cream and other medicines under the guidance of doctor. 2. Laser treatment: laser can reach the deep layers of the skin and destroy the melanin cells, so as to lighten the spots. Age spots can be treated with carbon dioxide laser, freckles and chloasma can be removed by intense pulsed light and Q-tuning laser. Patients with melanin spots should pay attention to protection and avoid direct sunlight. It is recommended to go to regular hospitals for consultation to clarify the specific nature of the spots, and then follow the doctor’s instructions to use medication or choose laser treatment.