Fenofibrate can be taken for a long time. Lipid-lowering treatment is a long-term process and needs to be combined with a low-fat diet. In the process of taking Fenofibrate, the dosage of Fenofibrate needs to be adjusted according to the patient’s blood lipid level as well as renal function and side effects of the drug. The most common adverse reactions of fenofibrate are nausea, vomiting, abdominal pain, this gastrointestinal reactions are generally mild and can be tolerated by continuing to take the drug. Common adverse reactions include abnormal liver function, and liver function should be reviewed regularly during the course of taking the drug. Fenofibrate may also cause muscle pain, muscle spasm, muscle weakness, when the drug needs to be discontinued.