Uremia is equivalent to the end stage of chronic kidney disease, that is, chronic kidney disease stage 5, and kidney transplantation is preferred for treatment in this period. If the economic conditions permit and there is a suitable kidney source, kidney transplantation treatment is preferred. The quality of survival of patients after kidney transplantation is relatively high, almost the same as normal people. If the transplanted kidney develops problems after kidney transplantation, and then renal failure occurs after how many years, this is the time to enter renal replacement therapy, and the overall life expectancy will be much longer. If you can’t have a kidney transplant, the treatment is to choose replacement therapy, either peritoneal dialysis or hemodialysis treatment. Hemodialysis needs to be done three times a week for about four hours each time. Peritoneal dialysis needs to be done 3-4 times a day and can be done at home. Other aspects of treatment are the prevention and treatment of complications. Patients with renal anemia need to take iron supplements with polysaccharide iron complex, and erythropoietin needs to be injected subcutaneously to treat the anemia. If the combination of hyperparathyroidism, mineral metabolism disorders (low calcium, high phosphorus) need to take calcium acetate, alfacalcitol and other drugs to prevent complications.