Lung cancer is a common malignant tumor, which often causes neglect when it occurs. Its clinical manifestations are as follows: 1. Asymptomatic: Since the lung parenchyma is not rich in nociceptive nerves, most patients with early stage non-small cell lung cancer can be asymptomatic. Early symptoms: Non-specific, mostly cough, hemoptysis, chest pain, chest tightness, shortness of breath, fever and other respiratory symptoms, more than 50% of patients have cough complaints. 3.Late symptoms: direct invasion of tumor or metastatic lymph node compression of laryngeal nerve may cause hoarseness; direct invasion of tumor or metastatic lymph node compression of superior vena cava may cause edema of face, neck and upper limbs, varicose veins and capillary dilation in upper chest; invasion of pleura or dissemination of pleural cavity may cause pleural effusion, mostly bloody; large amount of pleural effusion may cause shortness of breath; invasion of pleura and chest wall; especially invasion of wall pleura may cause chest pain; brain metastasis may cause chest pain. Brain metastases can cause headache, nausea, vomiting and other symptoms of increased intracranial pressure and other neurological localization symptoms; bone metastases can cause limited bone pain, mostly persistent and progressively aggravated; liver metastases can cause right upper abdominal distension and pain; subcutaneous metastases can cause nodules palpable under the skin.