Wake up in the morning will lead to a calf sweat may be caused by high external temperature, calcium deficiency, leg injury, vegetative nerve dysfunction and so on. 1. External temperature is too high: If the temperature of the external environment is too high, it will lead to an increase in the secretion of sweat glands in the body, thus relieving the temperature of the body through the evaporation of sweat. The sweat glands in the lower legs are large, which can easily cause a lot of sweating. 2. Calcium deficiency: a large loss of calcium in the body will lead to neuromuscular contraction, diastolic function, resulting in the development of abnormal metabolic rate of the body, thus causing the phenomenon of waking up in the morning calf sweat. 3. Leg injuries: exercise without adequate warm-up preparations for strenuous exercise, will lead to soft tissue injury in the calf area, and sleep inadvertent movement will enhance the injury stimulus, resulting in sweat glands secretion, which will lead to a lot of calf sweating. 4. Vegetative nerve dysfunction: the body of the vegetative nerve disorders, will promote the sweat glands in the calves of a large amount of secretion, so that the calves sweat when waking up in the morning. There may be other reasons for this symptom, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or treatment.