Chronic pyelonephritis can be improved after active treatment, but chronic pyelonephritis is difficult to be completely cured. Once chronic pyelonephritis has an acute attack, although the patient’s symptoms can be relieved by antibiotic treatment, it is still difficult to be completely cured and prone to recurrent attacks. Patients with chronic pyelonephritis may be related to many underlying diseases, such as polycystic kidney, hydronephrosis, ureteral stenosis, etc. Though surgery can be used to carry out the related treatments, the effect is not always ideal. Chronic pyelonephritis is a chronic disease and may have persistent renal tubular function impairment. Patients should pay attention to regulation in daily life and drink more water to minimize the number of infection episodes. When chronic pyelonephritis occurs, it is recommended to consult a doctor in time and treat it actively under the guidance of a physician.