Hepatitis B vaccine Glaxo and domestic ones are generally not recommended to be mixed, and can be mixed under special circumstances. Both imported and domestic vaccines can stimulate the body to produce antibodies to prevent hepatitis B virus infection. If conditions permit, it is best not to mix the vaccines, and it is recommended that the same vaccine be given throughout the entire course to avoid vaccine-related adverse reactions. For some unavoidable special circumstances, such as a temporary shortage of vaccine supply, the need to go to a different place, but it is already time for vaccination, then you can follow the doctor’s advice at the vaccination point to mix the vaccine, which can also achieve the effect of prevention. After vaccination, it is necessary to be observed at the vaccination site for at least 30 minutes so that any adverse reactions can be dealt with in a timely manner.