The cardiac fossa in medical terminology refers to the area below the glabella. The organs adjacent to this area are the heart, the lower esophagus, the stomach, the gallbladder and the left lobe of the liver. If heart fossa pain is present, it is important to differentiate diseases such as heart disease, gastroesophageal reflux disease, peptic ulcer and hepatobiliary disease. Diseases that may be associated with cardiac fossa pain are as follows: 1. Cardiovascular system diseases: Cardiac vascular lesions or inflammatory lesions can cause the sensation of cardiac fossa pain. Coronary heart disease (angina pectoris, heart attack, etc.) can cause myocardial ischemia and hypoxia, causing the sensation of heart fossa pain. Infectious diseases such as myocarditis and pericarditis may also cause heart soreness. The heart fossa discomfort caused by coronary artery disease is mostly related to exertion, emotional excitement, full meals, etc. If it is angina pectoris, rest or nitroglycerin inhalation can relieve it. Viral myocarditis may be preceded by a history of upper respiratory tract infection, and arrhythmias are common. Symptoms of pericarditis are associated with breathing, coughing, body position or swallowing. Further diagnosis of cardiac problems can be made by cardiac enzymes, troponin, electrocardiogram, echocardiogram, coronary CT, cardiac MRI or coronary angiogram. 2. Digestive system diseases: GERD, peptic ulcer and biliary tract diseases may cause heart soreness. Gastroesophageal reflux disease is caused by the reflux of gastroduodenal contents into the esophagus causing discomfort. It is often accompanied by acid reflux and heartburn, and is worse when lying down or when abdominal pressure is elevated. Peptic ulcers often occur in the stomach and duodenum, and patients generally complain of epigastric pain, which has also been expressed as heartburn. However, digestive disorders are not significantly related to exertion, but are influenced by feeding and antacid therapy, among others. Upper abdominal discomfort is also caused by lesions in the left lobe of the liver or gallbladder lesions. It can be clarified by barium meal examination, gastrointestinal endoscopy or ultrasound and other examinations. 3, psychosomatic factors: cardiac neurosis and psychological factors. In the case of careful examination still can not find a clear cause can be considered under the cardiac neurosis and psychological factors caused. Since there are more organs in the heart fossa, patients should not diagnose themselves with medication based on symptoms alone, and it is recommended to consult a regular hospital.