Chemotherapy for advanced pancreatic cancer generally requires 4-6 cycles, of course, these 4-6 cycles are divided, such as every 3 weeks or 4 weeks, and anti-tumor angiogenesis drugs, such as bevacizumab, can be added to the chemotherapy at the same time. It is worth noting that the efficacy of chemotherapy for pancreatic cancer is limited and is usually evaluated every 2 cycles. If the efficacy is judged as SD (stable) or PR (partial remission) according to the efficacy evaluation criteria, the chemotherapy can continue to be used until the disease progresses or the side effects are intolerable, and if the efficacy is evaluated as progression after 2 cycles, it is necessary to switch to another regimen of chemotherapy or other treatment modalities, such as simultaneous radiotherapy.