The following side effects may occur after taking progesterone: 1. gastrointestinal reactions, some people may experience nausea, vomiting, etc. 2. local changes in the breasts, such as localized swelling and pain in the breasts or breast overflow. 3. may cause menstrual disorders, or even amenorrhea if you have been taking progesterone. 4. occasional allergic reactions, such as itchy skin, edema or generalized The appearance of drug rash. Progesterone is a prescription drug and can only be given under the guidance of a doctor, otherwise incorrect use of the drug may lead to a series of other discomforts. In addition, if there is a tendency to thrombosis or have thrombophlebitis, the drug is not recommended for treatment.