Chronic granulomatous inflammation is usually caused by two reasons, and the treatment varies according to the different reasons. First, some bacterial infection caused by systemic granuloma inflammation, this situation is best to take local tissue and secretions to do bacterial culture and drug sensitivity test, select sensitive antibiotics treatment, if not bacterial infection, is a systemic inflammatory reaction, you can use non-steroidal anti-inflammatory drugs, glucocorticoid drugs treatment; Second, the wound inside the foreign body retention, such as the contaminated foreign body after the injury, or surgical sutures present in the wound inflammatory reaction, this situation is generally removed foreign body. The inflammatory reaction occurs when surgical sutures are present in the wound, and the local granuloma can disappear slowly after the foreign body is removed.