The pain above the right buttock is commonly caused by lumbar disc herniation, and CT examination can be chosen in the acute stage to clarify the diagnosis. The main choice is physiotherapy, bed rest, local traction, massage and acupuncture, which can relieve the condition. It is also necessary to take oral pain relief and nerve nourishing drugs, and the application of aminoglutethimide tablets combined with B vitamins can significantly relieve the patient’s discomfort. In severe cases of lumbar disc herniation, if combined with spinal stenosis, further surgical treatment options are needed. In addition, some patients are caused by neurofibromas that occur locally, which can also manifest as pain and even palpable local masses with smooth surfaces and clear borders, and surgery should be chosen to remove the lesions.