The pain above the right buttock is commonly caused by lumbar disc herniation, and CT or MRI examination can be chosen in the acute stage to clarify the diagnosis. The main choice is physical therapy, bed rest, local traction, massage and acupuncture, which can relieve the condition. Oral pain relieving and nerve nourishing drugs are also needed, and the application of aminoglutethimide tablets combined with B vitamins can significantly relieve the patient’s symptoms of discomfort. In severe cases of lumbar disc herniation, if combined with spinal stenosis, further surgical treatment options are needed. In addition, some patients are caused by neurofibromas that occur locally, which can also manifest as pain and even palpable local masses with smooth surfaces and clear borders, and surgery should be chosen to remove the lesions.