Hairy gallbladder alone is not cancerous, but in cases of cholecystitis, gallstones combined with gallbladder hirsutism, the chances of cancer usually increase for an undetermined period of time. Patients with simple hairy gallbladder do not have the risk of cancer and do not need to worry about it, but patients who have some underlying diseases of their own. For example, cholecystitis, gallstones. When these causes of gallbladder roughness, patients need to pay attention. Some studies have shown that diameter ≥10mm, combined with cholecystitis or gallbladder stones, single polyps or non-tipped polyps, polyps with fast growth rate, adenomatous polyps, etc., have a tendency to become cancerous. The mechanism may be that inflammation, stones, etc. produce long-term stimulation to their own gallbladder wall, which may easily lead to cancerous transformation of gallbladder epithelial cells and increase the chance of cancerous transformation. However, the time for the gallbladder roughness to progress into gallbladder cancer cannot be determined. It can be as short as a few years or as long as more than ten years. It is recommended that patients should consult the Department of Hepatobiliary Surgery of their local hospitals, and the above views are for reference only.