Pain when swallowing saliva due to enlargement of one side of the tonsil may be caused by tonsil abscess or tonsillitis, tonsil tumor and so on. It is necessary to identify the cause, targeted treatment, including drugs, surgical methods for treatment. 1. Tonsil abscess: If the swelling and pain on one side of the tonsils is caused by tonsil abscess, you can take antibiotic drugs under the guidance of the doctor, such as cephalosporin and amoxicillin. If the tonsil abscess has formed, puncture is needed to draw out the pus around the tonsils. 2. Tonsillitis: If the patient is due to tonsillitis caused by tonsil swelling and pain, you need to take oral amoxicillin and other anti-inflammatory drugs under the guidance of the doctor, while you can use prednisolone and other drugs to play the role of swelling. If the patient’s tonsillitis recurrence, can be appropriate through the way of surgery will tonsils again removed. 3. Tonsil tumors: Tonsil tumors can also cause unilateral enlargement of the tonsils, accompanied by symptoms of pain. When this disease occurs, patients need to use surgery to remove the tonsil tumor as soon as possible, after the removal of the pathology examination should be carried out to clarify the diagnosis, to take the necessary comprehensive treatment plan. Tonsils on one side of the swelling, pain when swallowing saliva need to go to the hospital in time for standardized examination, medication and treatment.