Patients who experience sore eyes after applying makeup usually suffer from blocked blepharoplasts or conjunctivitis. When applying make-up, if the patient’s eyes use too much cosmetic, it may block the opening of the blepharoplasty glands, resulting in the oily secretions in the blepharoplasty glands not being able to be secreted smoothly, leading to the instability of the tear film, which can increase the volatilization of tears, causing the patient to experience the uncomfortable symptom of dry eyes and soreness. Makeup, if the patient does not pay attention to eye hygiene, it may trigger eye infections, the formation of conjunctivitis, in the inflammation stimulation, the patient will also appear in the eyes of the discomfort symptoms of soreness, the patient needs to comply with the doctor’s instructions to use antibiotic eye drops treatment, such as levofloxacin eye drops, tobramycin eye drops and so on. It is recommended that patients who have significant eye soreness after applying makeup should seek timely medical attention to assess their condition and undergo treatment under the guidance of a doctor.