The common metastatic pathways of advanced gastric cancer are as follows: 1) direct infiltration, direct growth and invasion of neighboring parts, for example, cardia fundus cancer can easily invade the lower end of esophagus, gastric sinus cancer close to pylorus can invade the duodenum, and poorly differentiated infiltrative growth of gastric cancer can break through the outermost layer of gastric wall, i.e., plasma membrane layer, and spread to surrounding omentum, colon, liver, pancreas and other neighboring organs; 2) hematological metastasis, which occurs in the advanced stage of gastric cancer, in which the cancer cells enter blood vessels to spread to other parts of the body to form metastatic foci. In the late stage of gastric cancer, cancer cells enter blood vessels and spread to other parts of the body, forming metastatic foci, common metastatic organs include liver, lung, pancreas, bones, etc., among which liver metastasis is the most common; 3. Peritoneal implantation metastasis, when gastric cancer tissue infiltrates to the outside of the plasma membrane, the tumor cells are detached and planted in the peritoneal membrane and plasma membrane of the organs, forming metastatic nodes. Female gastric cancer patients can develop ovarian metastatic tumor; 4. Lymph node metastasis, which is the main metastatic pathway of gastric cancer. The lymph node metastasis rate of progressive gastric cancer is as high as 70%, and lymph node metastasis is also possible in early stage of gastric cancer. The lymph node metastasis rate of gastric cancer is related to the infiltration depth of cancer foci. Lymph node metastasis of gastric cancer is usually gradual, but jumping lymph node metastasis may also occur. That is to say, the lymph nodes at the first station have no metastasis, while the lymph nodes at the second station which is more distant develop metastasis. End-stage gastric cancer can metastasize to left supraclavicular lymph node via thoracic duct or to umbilicus via hepatic round ligament, so there are many aspects of gastric cancer metastasis.