Salvage chemotherapy for advanced breast cancer mainly includes the presence of extensive metastases, especially visceral metastases, such as rapid progression of liver and lung disease, and then the lack of effect of endocrine therapy. The drugs that can be chosen mainly include anthracyclines, mainly adriamycin and epothilone. Paclitaxel drugs are mainly paclitaxel, polyene paclitaxel. Antimetabolites are mainly capecitabine, gemcitabine. Then there are the Vincristines, Vincristine, Vincristine. The alkylating agents mainly include cyclophosphamide, platinum, mitomycin, and the others are mainly etoposide. Combination regimen CAF, AC, AT, XT regimen, NP regimen, GT regimen can be chosen. Generally anthracycline therapy failure can choose program XT, is capecitabine combined with paclitaxel, and then the GT program, gemcitabine combined with paclitaxel. There is no standard regimen to recommend for general paclitaxel failure. The drugs that can be considered are capecitabine, vincristine, gemcitabine and platinum-based chemotherapy alone or in combination.