Inguinal lymph node swelling and pain may be caused by a variety of factors, including localized infection of the lower limbs, chronic lymphadenitis, tuberculous lymphadenitis and so on. The specific cause should be decided according to the patient’s personal situation, and it is recommended to consult a doctor in time for examination and clear diagnosis. 1. Localized infection of the lower limbs: when there is localized infectious inflammation in the lower limbs, it may lead to swelling and pain in the inguinal lymph nodes. 2. Chronic lymphadenitis: when chronic lymphadenitis occurs in the groin area, inguinal lymph nodes will be enlarged and painful. Usually the diameter of the lump is not more than 2-3 centimeters, and it can be reduced after receiving anti-infective treatment. 3. Tuberculous lymphadenitis: In inguinal tuberculous lymphadenitis, patients in addition to inguinal lymph node swelling and pain, there will be fever, fatigue, excessive sweating and other systemic symptoms, usually accompanied by pulmonary tuberculosis. The presence of inguinal lymph node swelling and pain should be timely consultation, under the guidance of the doctor treatment.