Drugs for hyperthyroidism can generally be taken on an empty stomach or after a meal, such as hyperthyroidism combined with gastrointestinal disorders, it is better to take the drug after a meal, while other cases can be selected according to their own situation, it is recommended to consult a doctor. Drugs for the treatment of hyperthyroidism mainly include thiouracil (propylthiouracil, methylthiouracil) and imidazole (methimazole), the main mechanism of action is to reduce the synthesis of thyroid hormones. These antithyroid drugs, which are mainly absorbed through the gastrointestinal tract, may trigger gastrointestinal reactions such as nausea, vomiting and epigastric discomfort, as well as adverse reactions such as skin rash and granulocytopenia. For patients with hyperthyroidism combined with gastrointestinal diseases, such as combined chronic gastritis, reflux esophagitis, etc., can be taken after meals to reduce the stimulation of the drug on the gastrointestinal tract and reduce the adverse reactions. The appearance of hyperthyroidism, it is recommended to seek timely medical treatment, the drug needs to be taken under the guidance of a professional doctor.