1.Reduce activities before the wound stops bleeding; avoid lifting weights, lifting high, throwing bladder hard, doing pull-ups, lifting dumbbells, etc.; daily life will not be affected. 2.Reduce the activity of the arm on the puncture side within 24h when bathing, be careful not to get the auxiliary material wet. Before bathing, you can use cling film to wrap the catheter tightly and use adhesive tape on the top and bottom, check whether the dressing is wet after bathing, and replace it in time if it is wet. 3.Replace the patch once every seven days, replace the heparin cap, and perform positive pressure flushing of PICC. 4, 1 week after placement to promote blood circulation can do more fist movement, arm can be raised flat or lateral, as little as possible to do the elbow flexion movement. 5.When doing the contrast examination, remind the doctor not to push the contrast agent through the PICC tube at high pressure. 6, pay attention to observe: whether there is blood in the heparin cap and catheter, if there is blood, timely replacement to avoid blocking the tube. 7.When the heparin cap is lost, please fold the catheter temporarily and fix it on the skin with tape, and replace it at the hospital in time. 8.When swelling and pain occur in the arm or arm neck on the side of placement, go to the hospital promptly.