Hiccups are medically known as “eruptions”. Occasional hiccups are not a problem, but hiccups lasting longer than 2 months are considered to be persistent hiccups. The occurrence of intractable hiccups often causes great suffering and can even lead to death due to the severe impact on normal life and the heavy mental and physical stress. Between our thoracic and abdominal cavities, there is a thick, hat-like muscular membrane, the diaphragm, which separates the thoracic and abdominal cavities. Like all organs, the diaphragm is innervated and can receive various stimuli as well as contractions on the order of a “higher nerve”. The sudden contraction of the diaphragm, followed by the immediate closure of the larynx, and sometimes the contraction of the soft palate and auxiliary respiratory muscles, are coordinated by the medulla oblongata and hiccups are produced. The common name “hiccups” is a good one. Not only does it describe the symptom, but it also tells us about the direct organ that produces the symptom – the diaphragm. 1. General therapy: 1. Deep inhalation followed by breath-holding method: The use of deep inhalation followed by rapid forceful breath-holding or placing a paper bag around the nose and mouth creates a small environment of increased local carbon dioxide to stimulate the respiratory center and eliminate pathological excitement by increasing the concentration of carbon dioxide. 2.Acupressure on the auricular foot method: The patient is placed in a supine position, the operator is located on the top side of the patient’s head or facing the patient, and presses the auricular foot on both sides of the patient with the belly of the two thumbs simultaneously, from light to heavy, and continues to press until the termination of the eruption. 3.Press on both eyeballs: The patient closes the eyes, the operator places both thumbs on the patient’s bilateral eyeballs and moderately rubs the upper part of the eyeballs in a clockwise direction until the eruption stops. This method is mostly used for patients with upper abdominal surgery, but it is contraindicated for patients with glaucoma and high myopia, and should be used with caution for patients with heart disease. 4, swallowing smoke method: with a long round cardboard box, one end open (such as the cardboard box with adhesive tape), ignite the confetti with fire, put it into the box, so that it goes out to produce smoke, immediately press the opening of the box around the lips of the patient’s mouth, leaving the nostrils, ask the patient to open his mouth like eating food action, the smoke swallowed, but do not use the method of suction, 1 to 2 minutes to stop the erratic. 5, tongue pulling method: the patient to take a supine, semi-recumbent or sitting position, the whole body relaxed, stick out the tongue, the operator with a wet towel or sterilized wet gauze wrapped around the patient’s tongue, holding the hands to pull outward to the patient slightly painful for about 30 seconds, release the tongue body reset, the total efficiency of up to 100%. 6.Interference method: Interfere with normal breathing, such as: ask the patient to sneeze, cough, hold the breath or hyperventilation or use a suction tube along the nasal cavity to stimulate, etc. Second, drug treatment (specific medication, please combine with clinical, by the doctor’s face to face guidance shall prevail): (a) Western drug treatment: 1, acetazolamide: acetazolamide is also called vincristine. The drug has the effect of inhibiting the vagus nerve and phrenic nerve, and can be used to treat intractable eructations caused by liver cirrhosis, abdominal tumors, pulmonary heart disease and cerebral infarction. Its usage is to take 0.25 to 0.5 grams five times a day. It should be noted that individuals may experience mild dizziness and drowsiness after taking the drug, but these symptoms will disappear after stopping the drug. 2, Thorazine: The drug has the effect of inhibiting phrenic nerve excitation, can be used to treat stubborn erratic caused by encephalitis, cerebral infarction and other diseases. Its use is: 1 to 2 times a day, each time to take 25 mg. 3.Doxepin: This drug has the effect of lowering the vagus nerve tension and inhibiting the spasm of the diaphragm, and can be used to treat intractable erratic reflux caused by gastrointestinal distension, digestive tract tumor, encephalitis, cerebral infarction and other diseases. Its usage is: take 25 mg once or twice a day. In addition, patients with regular episodes of intractable eruption can take the drug half an hour before the onset of eruption. 4.Lidocaine: This drug has the effect of regulating the function of plant nerves and reducing the excitability of phrenic nerves, and can be used to treat intractable erratic reflux caused by gastrointestinal flatulence, digestive tumors and other diseases. Its use is: 50-100 mg of lidocaine added to 40-100 ml of 5% glucose solution for intravenous injection. 5, codeine phosphate: This drug has the effect of relieving diaphragm spasm, and can be used to treat intractable erratic reflux caused by uremia, cirrhosis, gastric cancer, acute gastritis, cerebral infarction and other diseases. Patients with intractable erratic can take 0.03g of the drug for the first time, then observe for half an hour, if the symptoms of erratic do not reduce after half an hour, you can take 0.03g of the drug, then observe for 6 hours, if the symptoms of erratic have disappeared after 6 hours, there is no need to take the drug again; after 6 hours, if the symptoms of erratic only reduce or still no sign of improvement, then the patient should take the drug continuously for 2 to 3 days. 3 days, can take 3 times a day, each time to take 0.03 grams. 6, ephedrine hydrochloride: The drug has the effect of inhibiting phrenic nerve excitation, and can be used to treat intractable erratic reflux caused by abdominal surgery. Its usage is: 3 times a day, 10-30 mg each time, the interval between the two doses should be more than 6 hours. It should be noted that patients with high blood pressure and children under 8 years of age should use this drug with caution. 7, haloperidol: the drug has a sedative effect, can be used to treat a variety of cerebrovascular disease caused by the intractable erratic. Its use is: 2 times a day, each time to take 5 mg, can be taken for 2 to 3 days. 8, Ritalin: The drug has the effect of inhibiting phrenic nerve excitation, can be used to treat intractable erratic caused by gastrointestinal flatulence, encephalitis, cerebral infarction and other diseases. Its use is: each intramuscular injection of Ritalin injection 20 mg, can be repeatedly injected, the interval between two injections should be more than two hours. It should be noted that this drug should be prohibited for patients with hypertension, glaucoma and epilepsy. 9.Huachanin: This drug can regulate the central nervous system of human body and has certain anti-tumor effects, and can be used to treat recalcitrant circumferential eruption caused by stomach cancer, liver cancer, coronary heart disease, cerebral infarction, pulmonary heart disease and other diseases. Its usage is: 2~4ml of Huachanin injection per intramuscular injection, 2~3 times a day. The drug can be stopped within 3 days after the cessation of the erratic symptoms in general patients, while cancer patients should be continuously injected with the drug for 2 to 4 months. 10, cardiac pain: The drug has the effect of inhibiting phrenic nerve excitation, and can be used to treat intractable erratic reflux caused by gastrointestinal distension, pleurisy, pneumonia and alcoholism. Its usage is: take the drug under the tongue after chewing it up, 10 mg each time, twice a day. (B) Chinese medicine treatment: Chinese medicine treatment should be distinguished from cold, heat, deficiency and concurrent symptoms, and the treatment should be based on harmonizing the stomach, lowering the rebellion, calming the err, and also on supplementing the deficiency and attacking the real, warming the cold and clearing the heat, activating blood circulation, relieving blood stasis and relieving liver depression. The following are some representative formulas: 1.Xuanduodaioche Tang with addition and subtraction; 2.Bingxiang Persicaria Tang with addition and subtraction; 3.Hematopoeia and Stasis Tang with addition and subtraction. The treatment of stubborn erratic is sometimes ineffective or inefficient with western medicine only, or it is easy to relapse after it is effective at that time, while the combination of Chinese and western medicine treatment has satisfactory long-term treatment effect. Acupuncture therapy: 1, acupuncture therapy: acupuncture therapy for the treatment of intractable erratic, can often achieve better results. 2, acupuncture point injection therapy: It is reported that, take the bilateral diaphragm Yu, Nei Guan, foot San Li points, by lifting, inserting, twisting and other techniques, back to draw no blood slowly injected chlorpromazine, the total efficiency of 96%; some authors treat 50 cases of recalcitrant erratic patients, through the double Houxi point injection of haloperidol 2.5mg, and intravenous injection of ephedrine 15mg, plus scopolamine therapy (intravenous injection of scopolamine 1.2mg before going to sleep), the results of treatment 1 time mg), the results of treatment 1 erratic disappeared 20 cases, the total effective rate of 96%. Another method is to take the bilateral Neiguan and Foot Sanli points and use Kakuti Tang with isoprostanes injection, resulting in a total effective rate of 96.42%. In conclusion, the treatment of persistent erratic is first of all etiological treatment, pay attention to the following points: 1, active treatment of the original disease, to find the cause; 2, for different individuals, choose the appropriate treatment; 3, emphasize the combination of Chinese and Western medicine treatment.