Organophosphorus poisoning, mostly seen in the misuse, spray laborers, can enter the body through the skin mucosa, respiratory tract, digestive tract a variety of ways to inhibit acetylcholinesterase activity, thus causing symptoms of poisoning, poisoning to do the following: First, quickly remove the poison, immediately get out of the poisoned environment, quickly remove contaminated clothing, with soapy water or water, clean the contaminated skin, hair, nails, etc.. In case of accidental organophosphorus poisoning, gastric lavage is required to reduce the absorption of the poison and promote its discharge, and call 120 immediately. b. Remove respiratory secretions to prevent asphyxiation, and administer oxygen, mechanical ventilation if necessary, and give cardiopulmonary resuscitation to those in cardiac arrest immediately. c. Apply cholinesterase compound to prevent the poisoning. Third, apply cholinesterase complexing agents, such as chloroexfoliation and iodine exfoliation; choline receptor antagonists, such as atropine and long tocopherol, etc. The two are often used in combination, and different doses can be taken according to the symptoms of poisoning. Fourth, symptomatic treatment, deal with various complications, such as acidosis, cardiac arrhythmia, etc. V. Close observation of changes in the condition should be made to avoid recurrence of the condition.