Some moles have a natural tendency to become malignant, which may be unchangeable, i.e. the so-called fate, but there are also many moles that do not become malignant but become cancerous due to repeated inappropriate stimulation, such as mole spotting or indiscriminate cutting at street stalls or irregular medical institutions for cosmetic reasons. If you want to get rid of them for cosmetic purposes, you must go to a regular department (mainly dermatology or cosmetic surgery) in a regular hospital for standardized treatment (usually complete excision), as improper treatment may induce malignant transformation and rapid growth of pigmented moles. Of course, even if it is not for cosmetic purposes, there are moles that should be considered for treatment, such as moles in places prone to repeated abrasion, for example, if the original pigmented mole is found to show some of the following changes, it is recommended to go to the hospital for regular consultation and treatment. The early manifestation of skin melanoma can be summarized as ABCDE law A (asymmetry) asymmetry: one half of the pigmented spot looks asymmetrical with the other half. B (border irregularity): The edges are uneven or have cut marks or jagged teeth, unlike normal pigmented nevi which have smooth round or oval outlines. C (color variation): Normal pigmented nevi are usually monochromatic, while melanoma mainly appears as dirty black, but can also have brown, brown, brown-black, blue, pink, or even white colors. D (diameter): Pay attention when the diameter of pigmented spots is larger than 5~6mm or when the pigmented spots grow significantly. Melanoma is usually larger than ordinary moles, so pay attention to pigmented spots larger than 5mm in diameter, and pigmented moles larger than 1cm in diameter are best evaluated by biopsy. E (elevation) augmentation: In some early melanomas, there is a slight augmentation of the entire tumor body. The only shortcoming of the ABCDE rule is that it does not take into account the rate of melanoma progression, that is, the tendency for significant changes to occur within a few weeks or months. Early-stage cutaneous melanoma that progresses further can develop ulcers, recurrent failure to heal, lymph node metastases, surrounding satellite lesions, and even distant metastases (lung, liver, bone, brain, etc.). The above is for reference only, no matter what, please keep in mind two words: ordinary moles should not be treated informally and casually; treatment of moles must be handled in regular hospitals.