Holding urine, medically known as compulsory urinary retention, begins to feel the urge to urinate when the bladder accumulates close to 200cc of urine; when the urine approaches 400cc, there is a strong urge to go to the toilet, and well, the holding begins. Continue to hold it, and the urine reaches 500-600cc, and the muscles that control urination swell and relax. At this point, you feel that you can continue to hold it until the urine in the bladder reaches the alert value: up to 800cc, at which point you have to “pour out”. The first: urinary tract infections Long-term holding urine, urine can not be flushed away bacteria, a large number of bacteria gathered in the urinary tract, may cause urinary tract infections. Women’s urethra is short and adjacent to the vagina, making it more vulnerable to contamination. The second: pyelonephritis The pressure of the urine stored in the bladder is too much, which can lead to urine reflux back to the ureter and renal pelvis, and if there are bacteria in the urine, it can easily lead to pyelonephritis. The third: prostatitis. Some studies have shown that bacteria from the urinary system can cause prostate infections by traveling backwards through the prostate ducts to the prostate gland. Fourth: Increased incidence of bladder cancer Some studies have shown that the number of urination is closely related to the incidence of bladder cancer, and the lower the number of urination, the greater the risk of bladder cancer. Because holding urine increases the time of action of carcinogenic substances in urine on the bladder, people who have the habit of holding urine are 3-5 times more likely to develop bladder cancer than the average person. Fifth: bladder rupture When holding urine, the bladder wall becomes thinner due to expansion, so if there is an accidental impact, the bladder wall may rupture and a large amount of urine will enter the abdominal cavity, resulting in infection in the abdominal cavity, which can be life-threatening if not rescued in time. Sixth: frequent urination, incontinence prolonged urination will damage the bladder muscle tissue, so that the bladder muscle contraction ability is reduced, resulting in frequent urination, urinary incontinence. Seventh: holding urine hurts the “heart” Holding urine makes the heart beat faster, inducing arrhythmia and myocardial infarction and other problems. In the rapid emptying of urine, the vagus nerve reflex causes bradycardia, which can also induce urinary syncope.