Down syndrome is a trisomy 21 syndrome that is easily recognized because of its specific facial features, mainly the wide eye spacing, but there is no clear standard for how wide it is, because children have different face shapes, eyes and genetic variants, and the width of the eye spacing is different. The diagnosis is based on the DNA test of the child to determine Down syndrome, not on the width of the eye spacing. Other facial features that help determine Down syndrome include a low nasal root, small eye fissures, an upward sloping outer canthus, small ears, a tongue that often sticks out of the mouth, a short stature, and a head circumference that is lower than normal. The hand lines are only one horizontal line, called broken palm.