Current clinical trials have confirmed that the New Crown vaccine is not involved in hepatic metabolism, so there is basically no effect on hepatic fibrosis after injection of the New Crown vaccine. Although liver fibrosis does not belong to the contraindication scope of New Crown vaccination, it is not recommended to inject New Crown vaccine during the morbidity period if there are patients with acute liver diseases and liver function impairment, so as to avoid the expansion of adverse reactions after vaccination. In this case, you can first go to the hospital, complete the relevant examinations, and consult a professional doctor’s opinion before receiving the new crown vaccine. After New Crown vaccination, some people may experience vaccine reactions such as malaise and fever, which are normal. If the fever persists for many days, or if there are other symptoms of discomfort, it is recommended to consult a doctor immediately to find out the cause of the reaction and treat the cause to avoid aggravation of the adverse reaction.