Early diagnosis and early treatment of peptic ulcer is certainly important for relieving symptoms, promoting healing and reducing complications of peptic ulcer, but taking effective measures to prevent the occurrence of peptic ulcer and prevent the problem before it happens is even better than early treatment. Peptic ulcer is a global disease, common disease, its annual incidence of 1.1%-3.3%, the prevalence of 1.7%-4.7%, it is estimated that about 10% of the population in its lifetime suffered from this disease. The incidence of peptic ulcer disease is higher and can occur in all age groups, but is most common between the ages of 20 and 50. The introduction of H2 receptor antagonists and proton pump inhibitors has shortened the healing time of gastric and duodenal ulcers, but the problem of recurrence has not been solved. Many studies have shown that the recurrence rate of duodenal ulcers after 1 year is as high as 50% to 80%, with an average of 70%, and that the recurrence of gastric ulcers is roughly comparable to that of duodenal ulcers. From the above, we can see that peptic ulcer patients are mostly young adults, mostly, with recurrent disease, leading to labor attrition, and the number of sick people, the cost of treatment is huge, bringing significant losses and burden to the society and economy. Its complications are serious and the mortality rate is high, which poses a great threat to human life and health. Early diagnosis and early treatment of peptic ulcer is certainly important for relieving symptoms, promoting healing and reducing complications of peptic ulcer, but taking effective measures to prevent the occurrence of peptic ulcer and prevent the problem before it happens is even better than early treatment. What are the feasible aspects of peptic ulcer prevention? 1. Epidemiological studies show that the incidence and harm of peptic ulcer in developed countries is decreasing because of the peace period after World War II, the stability of people’s lives, rationalization of nutrition, reduction of labor load, and improvement of social welfare undertakings and medical technology. We can take inspiration from this and try to create a peaceful external environment, balanced nutrition and moderate work and rest to make the prevention of peptic ulcer possible. 2.With the in-depth research on the etiology and pathogenesis of peptic ulcer, people gradually realize that the occurrence of peptic ulcer is the result of the combined effect of smoking, alcohol,, mental factors, Helicobacter pylori, bile and other factors, so we can prevent against the etiology, quit smoking and alcohol, cultivate temperament, reduce the rate of Helicobacter pylori infection in the population, treat bile reflux, avoid taking the destruction of gastric mucosa, prevent the development and recurrence of peptic ulcer. It has been proved that the incidence and recurrence rate of peptic ulcer is significantly reduced by prevention through the above programs. 3. The rapid development of gastroscopy technology makes the early diagnosis of peptic ulcer. Early treatment becomes possible, so that further development of peptic ulcer can be prevented, complications can be prevented, and the purpose of secondary and tertiary prevention can be achieved.